Vathi or Vathy is the main harbor of Ithaca and lies at the head of a long inlet on the East coast, four miles south of Kioni and five miles south of Frikes. It is a popular destination for yachts of all sizes during the season, as it provides a number of berthing opportunities as well as good anchorage off the town.

Shelter in the harbor is relatively good in the prevailing west winds. The town is a good base for renting a car or scooter to visit the various attractions of the island.